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WikiGenes - DIAMINOPIMELIC ACID - 2,6 …

The diaminopimelic acid (DAP)-type peptidoglycan potently activates imd -dependent induction of antibacterial peptides [9]. Diaminopimelic acid, also formed by this enzymatic pathway, is an integral component of bacterial cell walls, thus making ASADH an attractive target for …

Microbial mediated sedimentary phosphorus mobilization …

BLC is an estuarine wetland system located between the Mississippi River and Bayou Lafourche and separated from the Gulf of Mexico by a chain of barrier islands (FitzGerald et al., 2004).In contrast to the WLD region, the Barataria Bay region represents an area of net wetland loss although new land and wetlands have been created upstream around the David pond diversion structure (Boesch, …

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National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, Eu …

Carriage of λ Latent Virus Is Costly for Its Bacterial ...

Author Summary Dormant bacterial viruses, or prophages, are found in the genomes of almost all bacteria, but their impact on bacterial host fitness is largely unknown. Through experiments in mice, supported by a mathematical model, we quantified the activity of Escherichia coli prophage λ in monoxenic mouse gut, as well as its impact on its carrier bacteria. λ carriage negatively impacted ...

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Targeting evolution of antibiotic resistance by SOS ...

The above-presented examples of mutagenic polymerases could be regarded as potential targets for inhibiting antibiotic resistance development ().The RecA surface, defined by residues 112–117, directly interacts with the amino acid residues on the surfaces of the UmuC subunit of PolV.The E.coli RecAD112R/N113R mutant protein exhibits an extremely reduced capacity for PolV activation and …

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Gamma-IR Resistance of Bacteria in Soil and Permafrost ...

Abstract Ionizing radiation is among the most important planetary factors that regulate the intensity and dynamics of biospheric processes. At the early stages of life on the Earth, short-wave radiation permeated the Earth surface. The evolution of the planet, corrected by fluctuations of cosmophysical factors, contributed to the development of the adaptation processes in the emerging ...

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Recombinational branch migration by the RadA/Sms …

RecA protein also shows a preference for poly(dT) (Bugreeva et al., 2005; McEntee et al., 1981), which may be because poly(dT) assumes a more flexible structure (Mills et al., 1999). The apparent K D of RadA binding to poly(dT) 30 is about 110 nM, …

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Mechanism of RecO recruitment to DNA by single …

RecO is a recombination mediator protein (RMP) important for homologous recombination, replication repair and DNA annealing in bacteria. In all pathways, the single-stranded (ss) DNA binding protein, SSB, plays an inhibitory role by protecting ssDNA from annealing and recombinase binding.

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Inactivation of prophage lambda repressor in vivo. -

A Bailone,A Levine,R Devoret : J Mol Biol. 1979 Jul 5;131(3):553-72. DOI: 10.1016/0022-2836(79)90007-X : 168 : 1979 ...

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DNA Damage Responses in Prokaryotes: Regulating Gene ...

Bailone A, Bäckman A, Sommer S, Célérier J, Bagdasarian MM, Bagdasarian M, Devoret R. 1988. PsiB polypeptide prevents activation of RecA protein in Escherichia coli. Molec Gen Genet 214: 389 – 395.

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Haemato-immunological responses and effectiveness of …

Streptococcosis and Motile Aeromonad Septicemia (MAS) are important diseases of tilapia, Oreochromis spp. and causes huge economic losses in aquaculture globally. The feed-based vaccination may be an alternative to minimize major infectious diseases in tilapia. Thus, this study aims to evaluate the haemato-immunological responses and effectiveness of a newly developed feed-based killed ...

Targeting protein arginine methyltransferase 5 in cancers ...

PRMT5 is the major type II arginine methyltransferase and forms large complexes with different binding partners such as WD-repeat-containing protein MEP50 (methylosome protein 50) .It can specifically methylate a wide spectrum of substrates, including histones and non-histone substrates .The histone substrates mainly consist of histone H2A residue Arg3 (H2AR3), H3 residues Arg2 (H3R2) and Arg8 ...

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Suppression of Lipopolysaccharide-Induced Inflammatory …

LPS can induce and accelerate oxidative stress along with the inflammatory cascade. Upon the LPS stimulation of macrophages, the production of ROS is also increased, contributing to the manifestation of inflammation, and overproduced inflammatory factors may promote excessive ROS production (Mills and O'Neill 2016; Liu et al., 2018).

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Bailone RL, Aguiar LK, Roça RO, Borra RC, Corrêa T, Janke H, et al. Zebrafish as an animal model for food safety research: trends in the animal research. Food Biotechnol. 2019a;33(4):283 – 302.